The Effects of aerobic training on Apelinergic system of heart tissue in aged rats

	Volume: 40 Year: 2018 Month: 9
Subject	Others
Title	The Effects of aerobic training on Apelinergic system of heart tissue in aged rats
Authors	Parvin Farzanegi; Masoumeh Habibian; Mirabdollah Tahramuzi; Maryam Keshvari;
Abstract	Background: The aim of this study was to determine the Effects of aerobic training on Apelinergic system of heart tissue in aged rats. Methods: In this study 14 elderly wistar rats with average age of 40-50 months old, were randomly divided into two groups: control and training. Swimming training was programmed 3 days /week, 30 min/day for 8 weeks. All rats were sacrificed 48 hours after the final training session and after 24 hours of fasting myocardial tissue, apelin and its receptor levels were determined using ELISA method. Results: No significant difference was found between control and experimental group apelin heart muscle tissue there (p=0.01). Also, the apelin receptor test for heart tissue between the two groups was significant (p=0.02). Pearson correlation analysis between apelin and its receptor in the control group was statistically significant inverse linear (p=0.01), But the test for the exercise group showed no significant relationship (p= 0.44). Conclusion: It is possible that aerobic training in older people with varying levels of apelin and its receptors in heart muscle tissue, improves the cardiovascular system of the people. Keywords: Aerobic Training. Apelinergic System, Heart Tissue, Rats
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